Cardiovascular safety of new inhaled medications for asthma and chronic obstructive pulmonary disease: a critical review from pharmacist perspective
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چکیده
Advances in drug development and design have significantly reduced the cardiovascular effect of these drugs, including improved receptor selectivity, direct pulmonary drug delivery, reduced systemic bioavailability, and improved elimination of the absorbed drug. In the past few years some new medications were marketed, including two long-acting beta-2 agonists (LABA; indacaterol, vilanterol); and three long acting anticholinergics (LAAC; glycopyrronium, umeclidinium, aclidinium). 1,2
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تاریخ انتشار 2016